"It was a major sacrifice on her part, and it meant a lot."

It doesn't have to be about major sacrifices.

There was a time when families would make major sacrifices to pay for children's college.

Most of the science educators in this group actually make major financial sacrifices to do their work.

To fit on the Game Boy major sacrifices had to be made.

While the tuition is low compared to the cost of other private schools, it represents a major sacrifice for many.

I've had to sacrifice that for the team and we've all made major sacrifices.

"It has been the major sacrifice of this election."

There were major and minor sacrifices at each month-end feast.

The major sacrifice would have been children, mostly.