It is specifically needed in the mammalian kidney as an osmotically-active compound which facilitates passive re-uptake of water into the blood.
The regenerative capacity of the mammalian kidney is limited compared to that of lower vertebrates.
In the mammalian kidney, the regeneration of the tubular component following an acute injury is well known.
It is not derived from blood plasma but is produced by the thick ascending limb of the loop of Henle of the mammalian kidney.
Calbindin-D28k was first shown to be present in the intestine in birds and then found in the mammalian kidney.
This antibiotic stands in sharp contrast to various other cephalosporins and to the structurally related penicillins in undergoing little or no net secretion by the mammalian kidney.
The mammalian kidney develops from intermediate mesoderm.
One well-studied example is the specializations of mammalian kidneys shown by desert-inhabiting species.
In the mammalian kidney they follow two markedly different courses, depending on the location of the glomeruli from which they arise.
Exposure to ochratoxins through diet can cause acute toxicity in mammalian kidneys, and may be carcinogenic.