Patients are considered to have either localized or metastatic disease.

New drugs allow people with even the most advanced metastatic disease to live longer.

A. Right now metastatic disease is not thought to be curable.

There is no standard chemotherapy for patients with metastatic disease.

After the men developed metastatic disease, the median time to death was an additional 5 years.

The remaining patients present with metastatic disease in either regional or distant sites.

Long term survival for metastatic disease may be less than 10%.

The lung is the most common site of initial metastatic disease.

In 103 men, or 34 percent, metastatic disease developed.

Only 34 percent developed metastatic disease during the study.