Another factor may be how close the metastatic site is to the place where the cancer began.

Distant metastatic sites may include the bones, lungs, and liver.

The prognostic factors found to be significant on univariate analysis were ECOG performance score, gender and number of metastatic sites.

Cancer cells often lay dormant at their metastatic site for a long period of time (lag period) before proliferating (invasive spread).

Survival by metastatic site is shown in Table 6.

The most common metastatic sites of hepatocellular cancer are the lungs and bone.

SCLC is fluorodeoxyglucose avid at the primary site and at metastatic sites.

Adequate local control for metastatic sites, particularly bone metastases, may be an important issue.

Stage IVB: All other metastatic sites, with one risk factor.

Stage IVC: All other metastatic sites, with two risk factors.