The methodological challenges sketched above are considerable, and seemed best tackled in a stage-by-stage manner.

As social scientists often work with many variables, determining the number of affected genes also poses methodological challenges.

There are significant methodological challenges in estimating these risks with precision.

The attempt to objectively evaluate the impact of microcredit on a global or a local scale is marred by numerous methodological challenges.

Design experiments: Theoretical and methodological challenges in creating complex interventions in classroom settings.

Current conceptual, technical, and/or methodological challenges in single cell analysis.

The most important methodological challenges of a survey methodologist include making decisions on how to:

Theoretical and methodological challenges when researching motivation in context.

G. Wächtershäuser (1997) The origin of life and its methodological challenge.

The purpose of the meetings was to address the challenges unique to establishing the optimal evidence base in surgery, including practical, methodological, and ethical challenges.