As director of the division of stomatology from 1958 to 1977, he began to identify and systematically describe those illnesses and correlate them with microscopic findings.
In one incident, a lab scientist wrote an incriminating report based on microscopic findings without actually bothering to look through a microscope.
Both macroscopic (from endoscopy) and microscopic positive findings are required to make a diagnosis.
It uses gross and microscopic findings along with the findings of in vivo radiological studies, and occasionally, specimen radiographs to diagnose diseases of the bones.
The diagnosis is usually confirmed by a surgical pathologist, taking into account the clinical presentation, microscopic findings, and other laboratory tests.
The clinical features and light microscopic findings were similar to those described in children with liver failure due to valproate or in Reye's syndrome.
On the muscle biopsy, there are two classic microscopic findings of dermatomyositis.
"There were numerous instances in which you failed to note pertinent microscopic findings," he wrote.
Clinical stage, however, as a prognostic factor must be supplemented by several gross and microscopic pathologic findings in surgically treated patients.
An asteroid body, is a microscopic finding seen within the giant cells of granulomas in diseases such as sarcoidosis and foreign body giant cell reactions.