Automobile trade has been the most nettlesome issue under the framework agreement reached by the two nations in 1993.
Probably the most nettlesome issue facing the 6.5-square-mile town is the development of low-income housing.
They correct the most nettlesome aspects of campaign financing by building on court precedent.
What posed the most nettlesome problem was graffiti: there was none.
Some have described these discussions as among the most nettlesome before Iraq regains sovereignty.
There you have it, a most nettlesome Independence Day choice.
He declined to specify which problems were most nettlesome.
The details emerged today as lawmakers tried to negotiate the remaining issues holding up a new state budget, with education spending among the most nettlesome.
Many people agree that it is the music division that is most nettlesome.
Perhaps the most nettlesome question for the Gore campaign is how to take advantage of the humming economy.