The mice did not live long, suffered from osteoporosis, had shriveled organs and did not bear up well under stress.
Dr. Donehower said that aging was hard to characterize and that critics might argue the mice were suffering from some subtle pathology different from aging.
The mouse lives longer but still suffers some symptoms.
The mice had suffered from a complete lack of photoreceptor cells in their retinas, and had been unable to tell light from dark.
Furthermore, mice deficient in the C3 protein do not suffer from severe disease following infection.
In the natural world, of course, mice rarely, if ever, suffer from cat allergies.
By comparison, normal mice almost never suffer from malignancies at that age.
However, mice with WISP3 knockout or overexpression are normal and suffer no apparent developmental defect.
The results showed the mice suffered drops in heart rate and other symptoms of SIDS, and many of the animals died at an early age.
A little skinny mouse suffers the humiliation of being kicked at the beach by a bully, some sort or medium-size carnivore.