Therefore, he hoped that the supporting text for this recommendation would include statements about the need for a large, multi-center trial in EDs.

The results of the multi-center clinical trials were published in 2008 reporting a 74% patient acceptance rate.

He is a researcher and a leader in several nationwide multi-center clinical trials.

In large, multi-center clinical trials authorship is often used as a reward for recruiting patients.

Treatment of bulimia with bupropion: a controlled multi-center trial.

In 2010, minocycline was found to be ineffective for humans in a multi-center trial.

Ubidecarenone in the treatment of mitochondrial myopathies: a multi-center double-blind trial.

But experts say that major, multi-year, multi-center clinical trials can be so large, expensive and time-consuming as to make it difficult to check conclusions.

Efficacy and safety were demonstrated in a single multi-center trial that enrolled 40 patients aged 2-19.

He thought a successful multi-center trial could lead to the creation of a standard of care.