Sphinx may act as a negative regulator of target genes.
There are two other negative regulators of cysteine.
Secreted fgl2 (sfgl2) plays a role as a negative regulator of the Immune response.
All together, these data indicate that proteases can function as both positive and negative regulators of angiogenesis.
GDF11 is closely related to myostatin, a negative regulator of muscle growth.
Nif genes have both positive and negative regulators.
Mdm2 is an important negative regulator of the p53 tumor suppressor.
Several negative regulators of Syk have been reported.
Egfl7 is a natural negative regulator of vascular elastogenesis.
This hypothesis is also supported by the findings about other negative regulators of plant photomorphogenesis.