In situ hybridisation studies have shown that human papillomavirus can be detected only within lesions and not in adjacent normal epithelium.

Smoking is associated with a significant and dose dependent decrease in the concentration of antigen presenting Langerhans' cells in the normal cervical epithelium.

The transition from normal epithelium to adenoma to carcinoma is associated with acquired molecular events.

This is in order to allow production of normal basement membrane and division of normal epithelium.

Occasionally non-specific staining was noted with AEC at the surperficial layers of normal epithelium demonstrating parakeratosis.

The data presented show that colonic carcinoma cells express ICAM-1 molecules on their cell surface in contrast with normal colonic epithelium.

CC arises by distinct morphologic changes from normal epithelium and progresses to carcinoma through a series of well-defined preinvasive lesions.

The expression pattern of RARB in normal epithelium is complex since the staining intensities are highly variable between nuclear and cytoplasmic compartments.

There was no normal epithelium to evaluate the expression in most CIN cases studied.

For RARB, staining in normal epithelium either nuclear or cytoplasmic or both were considered positive.