The γ 1 het and γ 1 null mice have no visible abnormalities and are fertile.

The CIDE null mice show decreased lipogenesis.

However, some double null mice survived into adulthood, and displayed smaller stature, skeletal lesions, and unusually small but functioning kidneys.

A sarcospan null mouse has recently been generated and appears to display a normal phenotype [ 22].

Seizures are likely due to altered firing of hippocampal neurons (KCNA1 null mice have seizures for this reason).

We report here long term retention of cochlear sensory neurons for at least 6 months, in particular in the cochlear apex, in Brn3c null mutant mice.

In addition, null mice show increased tissue damage and mortality following challenge with bacteria or endotoxin and are hypotensive under anesthesia yet normotensive in the conscious state.

IKK-α null mice have a truncated snout and limbs, shiny skin, and die shortly after birth due to dehydration.

Circadian rhythm is altered in null mice.

While null mice exhibit normal learning ability and short-term memory, long-term memory consolidation deficits have been demonstrated.