Particularly now, when he did know something of real significance.

The girl would only come here if she had something of significance to tell him.

But you don't learn anything of significance from the work.

My life will make a book of deep, human significance.

What he actually found was to lead to something of far greater significance to history.

"They want to bring some kind of significance into their lives."

Not for a matter of such significance, at any rate.

The issue was one of national significance, the state said.

I should like to single out four points of significance.

What you might think I'm doing is really of no significance to me.