Remember, your blood alone is not the only issue here.

The only issues are cost, and how best to do it.

For the moment, however, money is the only real issue in the race.

The only issue is whether the results are any good.

My only issue was having to do the theory again.

Drug prices are by no means the only issue in the campaign.

My only issue is that I would have to leave in 4 days!

This was, of course, not the only issue in the campaign.

But these are not the only issues in her book.

The only issue is how to turn it into action.