Establishing a farm board and possibly an agricultural district in Westchester, where zoning laws are both plentiful and painstakingly developed, could be a challenge, state officials say.

Shane and Reynolds felt that the formula for song selection and performance that they had painstakingly developed and rehearsed still served them well.

Though painstakingly developed, the characters do not have enough to do except watch and talk.

The redesigned mouse represents the most advanced example of a technique that has been painstakingly developed over the past decade by many investigators.

That includes the Netherlands, which more than any other country has painstakingly developed a division between "soft" and "hard" drugs.

She felt so much more competent and able now, more like the woman she had carefully and painstakingly developed.

There are various factors cited by owners of those particular properties - personal reasons being the most prevalent - but there is definitely no overall trend to abandon a region so painstakingly developed.

A vaccine, painstakingly developed by Merck scientists over many years and awaiting approval for use in this country, has been shown to be highly safe and effective in testing since the early 1980's.

None of the experience and sophistication that has been so painstakingly and carefully developed by NATO on both the political and operational fronts is apparent in any of these proposals.

"They are founded on new principles and new conceptions, which in turn are painstakingly developed by research in the purest realms of science!"