Advancing paternal age has been implicated in a number of possible health effects.

Until now, the problems known to occur more often with advanced paternal age were so rare they received scant public attention.

Increased paternal age has also been correlated to schizophrenia in numerous studies.

And it may be that advanced paternal age is associated with a mutation.

However, they report a significant effect of paternal age.

Researchers have started to investigate maternal and paternal ages as the root for autism.

Scientists have formulated at least two hypotheses to explain how paternal age might cause health effects.

However, two studies published in 1997 and 2000 failed to find a relationship between paternal age and Alzheimer's.

Before 1998, four studies had been published concerning a possible association between diabetes mellitus type 1 and paternal age.

A 2010 paper from Spain provided further evidence that average paternal age is elevated in cases of mental retardation.