Biotechnology manipulates that genome only fractionally - inserting, say, a gene for pesticide resistance.

In response to pesticide resistance, pest managers may resort to increased use of pesticides, exacerbating the problem.

Or a bacterial gene that confers pesticide resistance can be introduced into wheat or cotton.

Pests can develop a resistance to the pesticide (pesticide resistance), necessitating a new pesticide.

However, pesticide resistance is increasing.

Between 500 and 1,000 insect and weed species have developed pesticide resistance since 1945.

A similar situation occurs with pesticide resistance in plants and insects.

IPM uses a combination of chemical, cultural and biological controls to reduce spending on pesticides and to decrease pesticide resistance.

CYPs have also been heavily studied in insects, often to understand pesticide resistance.

Though commonly used, the pesticide approach often requires multiple visits and may not always be effective due to pesticide resistance and dispersal of the bed bugs.