One of the most potent compounds is the oxyiminomethyl derivative ST1481 that has the advantage to overcome drug resistance caused by transport systems.
For example, it is know that leukotrienes are potent chemotactic compounds.
Aflatoxin B1 is the most toxic and potent hepatocarcinogenic natural compound characterized.
Of course, such potent compounds had still to be assessed in animals, before they could be used in patients.
This is particularly useful when processing toxic or highly potent compounds.
It is still experimenting to determine the most potent compounds, its chief scientist, Mark Zoller, said.
Apart from being a potent toxic compound, it may also be used in therapeutic ways.
In 2007 few of the most potent compounds contain a proline mimetic cyanopyrrolidine P1 group.
The most potent compounds from this family, novichok-5 and novichok-7, are supposedly around 5-8x more potent than VX.