Researches suggest that among all potential mediators, a protein called Interleukin-1 is by far the most potent cause of the pain, joint inflammation and loss of cartilage associated with osteoarthritis.

Mr. Bush has said he is not seeking out Mr. Gorbachev as a potential mediator in the Gulf crisis.

Another model that is often tested is one in which competing variables in the model are alternative potential mediators or an unmeasured cause of the dependent variable.

Hence resistin is a potential mediator of insulin resistance in humans with acute inflammation.

Our data suggest that the biologically active amidated peptides that are potential mediators of these actions cannot be more than a small proportion of the total progastrin produced.

He was considered a moderate and a potential mediator between the military and more radical opposition elements.

Higher fasting insulin levels, the result of obesity and lower physical activity, have been proposed as a potential mediator of this increase in risk.

His paper, "WAF1, a potential mediator of p53 tumor suppression", which has been cited over 5,000 times, is among the top 10 most-cited papers of the 1990s.

But last week he visited Zambia and South Africa for talks with potential mediators in the conflict.

There is no reason to favour Turkey as the main potential mediator for a positive influence in the region.