"One is pure, the other contains an extremely powerful sedative."
"Faye said she gave you a powerful sedative to be sure you got a good night's rest."
I have just given you a rather powerful sedative.
The glare of the snow was like a powerful sedative, urging him to lie down, to forget everything.
I suspect she probably concocted a powerful sedative and added it to the reservoir.
I felt like I'd been slipped an overdose of a powerful sedative.
"And that's why I put a pretty powerful sedative in your coffee."
The only thing she gave me was an extremely powerful sedative.
To overcome this he received a prescription for a powerful sedative.
He might accidentally have given Grace a lethal dose of the powerful sedative.