These two paralogue proteins self-assemble in higher order structure helices and bind preferentially to phosphoinositide-containing membrane.
Agonists preferentially bind to and stabilize the R* state, thereby increasing effector activity.
They bind preferentially to the closed or inactivated state of Kv4.2 and Kv4.3 channels .
E2F-4 and 5 preferentially bind to p107/p130.
Making it bind preferentially to a certain level of gravitational curvature.
Probe specific amplification uses synthetic probes that preferentially bind to a target sequence.
It is capable of sensing membrane curvature by binding preferentially to curved membranes.
As a result, the toxin preferentially binds to the closed channels.
For example, Sialoadhesin preferentially binds α2,3 linkages over α2,6 linkages.
In effect, serine proteases preferentially bind the transition state and the overall structure is favored, lowering the activation energy of the reaction.