Each public company and each securities firm or representative deals with the principal regulator - the regulator in its home jurisdiction.

States are the principal regulators of insurance.

'Insulin is the principal regulator of fat metabolism'...

PTH is the principal regulator of serum calcium hemostasis.

Instead, the Ontario Securities Commission follows a "mutual reliance" policy in which it decides in each case whether to accept the decision of the principal regulator.

It also is one of the principal regulators of the banking system.

The bill also tilts in favor of the Federal Reserve as the principal regulator of banking activities.

The principal regulator is the Takeover Panel, a nongovernmental organization.

Bicarbonate (HCO ) transport mechanisms are the principal regulators of pH in animal cells.

Such problem plans have typically claimed to be exempted by Federal law from oversight by state officials, the nation's principal regulators of insurance.