Although the B-52A was the first production variant, these aircraft were used only in testing.

Only one production variant was built, the standard An-22 .

The last major production variant was the H-20, which entered into production in early 1944.

Improved production variant with new tail unit and more powerful engine, 1071 built.

The final production variant last one built in August 1944.

Initial production variant with external start system, 37 built at Tashkent.

The production variant made its first flight on 14 May 1999.

The endurance of the production variant is up to 20 hours.

The first production variant was the M-80 which was only made in small numbers.

Initial production variant with two 900 hp R-1830-64 engines, 60 built.