In Vienna, Schumann found himself beset by depression and professional disappointment.

And both carry with them a heavy weight of professional disappointment.

Mr. Cousteau's later years were marked by professional disappointments and personal losses.

"No," I said, and he looked at me with a practiced look of professional disappointment combined with anticipation.

It could be a personality flaw, a long series of personal or professional disappointments.

The remainder of his life was a succession of personal and professional disappointments.

But roles like those proved tantalizingly unavailable, and professional disappointment only made her private problems more consuming.

It traced the difficulties that female lawyers confronted as they encountered double standards and professional disappointment.

He waded through enormous professional disappointment before winning his first championship, in 1996.

But their personal problems, by this time, have become part of a larger pattern of social uncertainty and professional disappointment.