Renewed contact with the West precipitated a profound alteration of Japanese society.

If that happened it would only be as a consequence of a profounder alteration.

But it's also about a profound alteration that these scientists wrought in the way we look at reality.

The most profound alterations of the original novel's plot concern the character of Richie and his fate.

The status indices and symbols next to the cache weapon's icon changed, signifying a profound alteration in the weapon's condition.

It helped initiate British Pop Art and also attempted a more profound alteration of attitudes toward fine art.

This is a profound alteration of the Military Revolution thesis originally proposed by Michael Roberts in 1955.

Death psychologically, with the profound, sometimes irreversible alteration of the body's normal processes through inexcusable manipulation.

This marks a revolution and a profound alteration in some of the original tango forms.

"Their genetics haven't changed, but their lifestyles have undergone profound alterations," the authors said.