The case has already made a profound contribution to international law.

His profound contributions have so positively affected the times in which we live.

TIP Grandparents make profound contributions to their families, so take your role seriously.

While both these men had profound contributions to the Western mystery tradition, it appears neither was versed in it.

These artists made profound contributions to the development of American abstract painting.

But if that is our conclusion, then we miss perhaps the most profound contribution this story has to make to theology and to faith.

"Thank you for your profound contribution, Tommy," said Ruth.

It has been stated that "perhaps the institute's most profound contribution to conservation is the dissemination of information and methods learned in the field."

Strikes and student protests soon became more violent too, the Vietnam war making a profound contribution to the depth of the dissent.

Professor Vaidya's profound scientific contributions had phenomenal impact in journals and publications.