He walked round the precincts slowly, and a profound depression seized him.

He reached the house in a state of the profoundest depression.

We're living through a period of profound intellectual depression and it will eventually reach breaking point.

There's no question that profound depression is a disease.

Talking to his fellow soldiers also helped Myers, 24, bounce back from a profound depression, he said.

It was Britain's largest and most profound economic depression of the 20th century.

In the fall of 1987, she sank into a profound depression and thought about suicide.

It won't come as a surprise that I plunged into a profound depression, which lasted for several weeks.

A profound depression set in at the same time, despite the fact that she knew her bowel symptoms could now be controlled quite easily.

Over the summer of '68, he sank into a profound depression.