Activation of MMP-2 requires proteolytic processing.
Due to its aminopeptidase activity this enzyme may play a role in the proteolytic processing of bioactive peptides in those tissues where it is expressed.
In brief the protein information, its domain structure, protein termini, terminus modifications and proteolytic processing of and by other proteins is listed.
It is synthesised as an inactive precursor, prekallikrein, which must undergo proteolytic processing to become activated.
HBeAg is produced by proteolytic processing of the pre-core protein.
However, familial Alzheimer disease is likely to result from altered proteolytic processing.
Caspase-1 is important for the proteolytic processing of the pro-inflammatory cytokines IL-1β and IL-8.
The virus matures after proteolytic processing by the viral protease (PR).
Post-translational proteolytic processing of N-Oct 3 may be possible.
Most of the peptides appear to be derived from proteolytic processing of the milk proteins β-casein and a β-casein homolog.