In both cases, weakness eventually progresses to include both distal and proximal muscles.
There the tip developed as a hand but all the more proximal structures were absent, and so there were no muscles proximal to the hand.
Another condition associated to mutations in this gene is paraspinal and proximal muscle atrophy (doi: 10.1016/j.nmd.2013.04.003).
The "waddling" is due to the weakness of the proximal muscles of the pelvic girdle.
The proximal muscles (those closest to the trunk) are predominantly affected; this leads to difficulties climbing stairs and rising from a sitting position.
Palmer's method involved "muscle motion" in which the more proximal muscles of the arm were used for movement, rather than allowing the fingers to move in writing.
The nomenclature of these extensions derives from their location and proximal muscles.
Gowers' sign is a medical sign that indicates weakness of the proximal muscles, namely those of the lower limb.
By the age of 70, these losses occur in both proximal and distal muscles.
This disease affects the proximal muscles of the head, shoulders, and neck.