In the months before he was admitted to the hospital, Michael lost over 45 pounds and stopped his pubertal development.

Further research is needed to assess the impact of these compounds on pubertal development.

The sequence of events of pubertal development can occasionally vary.

Hyperthyroidism has unique effects in children on growth and pubertal development, e.g. causing epiphyseal maturation.

"If a girl's pubertal development seems to stop or reverse itself, that may be a sign of an eating disorder," Dr. Lerner said.

Childhood Crohn's disease is often complicated by retardation of linear growth and pubertal development.

Only patients at Tanner stage 1 or 2 of pubertal development when initially assessed were included in this study.

They quite often seek evaluation when classmates or friends undergo pubertal development and growth, thereby accentuating their delay.

Therefore, these guidelines also apply to treatment of HIV-infected youth who have not yet completed pubertal development.

Androgens are important in fetal development as well as in pubertal development.