Activation of CD47 with TSP-1 in wild-type cells inhibits proliferation and reduces expression of stem cell transcription factors.
Mutations affecting GPI that reduce expression of CD59 and decay-accelerating factor on red blood cells result in paroxysmal nocturnal hemoglobinuria.
IL-1β coordinately reduced expression of integrin a1, a cell-adhesion molecule that chondrocytes use to bind to type II collagen [ 48].
This reduces expression of tumour necrosis factor (TNF), interleukin 1α and β, and interleukin 6.
Ceftriaxone has been shown to reduce the development and expression of tolerance to opiates and other drugs of abuse.
Fasting reduces expression of this aquaporin independently of vasopressin.
The new face could worsen the appearance and reduce facial expression.
A binding site for PEBP2/CBF factors has been identified between -158 and -90 and disruption of this site reduces expression.
A methyltransferase, G9a, was found to have reduced expression in the nucleus accumbens in cocaine addicts, therefore causing reduced H3K9me2 levels.
Experiments have shown this reduces α-Gal expression by 70%.