Nodes still represent genes and connections between them regulatory influences on gene expression.
What the virus expert sees are segments of the genetic material that may represent genes or may be silent.
This would manifest itself in a distribution of signal intensity ratios as a bimodal distribution representing present and absent genes.
Approximately one third of these transcripts represent uncharacterized and unnamed genes and were not previously known to be regulated by androgen.
The remaining 34% did not match Release 3 annotations, leading to the possibility that some or all of these may represent novel genes.
For instance, in our example, we treat cluster 1 as representing genes with changed expression whereas clusters 2 and 3 consist of genes without expression changes.
An example of this is a centroid that represents genes that were strongly induced by amino-acid starvation (cluster 2 in Figure 5b).
They more likely represent genes that are either adapted to or carry the marks of frequent lateral transfers.
How shall we represent "genes" in our computer model?
Oligo probes can be designed to represent individual genes by exploiting even small polymorphisms.