However, failures of Rifampin treatment have also been reported and resistance can develop.

And experts worry that resistance to Synercid could develop as well.

The big question about Synercid is whether, or when, widespread resistance will develop to it.

Despite this precaution, some resistance has developed to all of these drugs because to their widespread use.

Additional confusion can occur if resistance develops and creates a need to change drugs.

Another theory is that the resistance developed from inappropriate use of the two drugs, which are widely available over the counter in many countries.

They reached the citadel and broke in before resistance developed.

If only a few active substances are used, resistance to pesticides will develop more quickly.

The Harvard team had originally reported that such resistance did not develop after 10 generations.

The dam was planned decades ago, but resistance has developed against the project.