She came to the conclusion that horses respond best to women.

A man can respond best to short and direct statements.

For whatever reason, desserts seem to respond best to reinvention.

Finally, subordinates respond best to coaching if they are motivated.

She has found that students respond best when they have a relationship with her.

She had noticed that the girl seemed to respond best to direct statements.

Nature, he suggests, will best respond to "a logical and carefully thought out questionnaire".

He seems to respond best in important games, especially when foes try to intimidate him.

"The kids will respond best to people they trust."

We do not know what is happening in our environment or how we might best respond to this challenge.