However (+)-naloxone was also found to reduce the effects of stimulant drugs, suggesting additional actions beyond TLR4 antagonism (possibly as a sigma receptor antagonist), that might potentially result in unwanted side effects or drug interactions.

Another important area is the potential for improper administration and use of potentially inappropriate medications, and the possibility of errors that could result in dangerous drug interactions.

Taking certain medications with this product could result in serious (rarely fatal) drug interactions.

Concomitant therapy of ritonavir with a variety of medications may result in serious and sometimes fatal drug interactions.

Diltiazem and verapamil inhibit hepatic cytochromes CYP3A4, CYP2C9 and CYP2D6, possibly resulting in drug interactions.

This may result in significant drug interactions which may put these people at a heightened risk for side effects that may be masked by the positive effects or side effects of antipsychotic drugs themselves.

Certain medications taken with this product could result in serious (rarely fatal) drug interactions.