Mouse studies suggested an essential role of this protein in spermatogenesis.
The generation of desmuslin null animal models will also contribute to the understanding of the role of this protein in muscle and cardiac disease.
"We've really just begun to understand the role of this protein in the pathology of Alzheimer's."
The role of this protein in Plasmodium is not currently known.
The role of this protein in G1-S transition has been recently questioned as cells lacking Cdk2 are reported to have no problem during this transition.
While most of these proteins are involved in splicing, the role of this particular protein is not yet known.
However, the exact role of this protein in intracellular transport of bile acids and cytoprotection was undefined.
Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis.
Dr. Lindquist and her colleagues believe they have come close to defining the normal role of this protein.
There is currently very little information about the cellular role of this protein.