Hampton's loss would be a serious blow to the team.
The ruling was a serious financial blow to the League.
"This is a serious blow to the peace process," the Government said in the statement.
Could this be a serious blow to American efforts to control its enemies in the region?
"We may have dealt him a more serious blow than I thought."
A person who is quickly back on his or her feet after a serious blow.
But, he added, that would not constitute a serious economic blow.
"The investigation could be serious blow to the city's future as a financial center."
A strike would be another serious blow to a company already in crisis.
The loss of the city and its 5,000 troops was a serious blow to the American cause.