Sleep did not relieve Titov's serious discomfort; he still felt very ill after awaking.

Depending on the exact site, this can cause sensations ranging from mild irritation to serious discomfort.

"This is amazing," he chokes, but I know that he's in serious discomfort.

In rare individuals an atypical response may result in serious discomfort, disease, or injury.

If you don't take time and care in selecting your walking shoes, you may be in for some serious discomfort.

It left a lot of pale skin exposed to the sunlight, and I knew she'd be bright red and in serious discomfort before nightfall.

Also animals can get trapped in the rubbish and be in serious discomfort.

Saberhagen, meanwhile, was said to be unable to extend his arm fully without serious discomfort.

In its later stages, this was a match between two men in serious discomfort.

But you are a tourist - more or less - and I expect you to ask questions, and will steel myself against any serious discomfort.