Mutations in some of these Pax genes lead to severe developmental abnormalities.
The couple had had a baby boy born with severe developmental abnormalities who died after a short and distressful life.
Infant has no severe abnormalities that affect ability to suck/feed or to learn.
However, 10% of those with more severe or additional abnormalities die from it.
The severe abnormalities ranged from heart defects and a missing kidney to the development of a brain outside the skull.
In it she recounts trying to come to terms with the fact that two of her four sons had been born with severe abnormalities.
However, the child was born with a variety of severe congenital abnormalities, requiring multiple surgeries.
Hindus generally tend to support abortion in cases where the mother's life is at risk or when the fetus has a severe developmental abnormality.
Major surgery and general anesthesia can cause severe metabolic abnormalities in patients with type 1 diabetes.
The last treadmill test in January 1978 "indicated severe abnormality and was positive for heart disease."