The further from one's true self the semblance was, the more severe the resultant depletion.

The largest ozone hole ever observed was in 1992, when the area of severe depletion over Antarctica covered more than 9.4 million square miles.

The key toxic effect of the drug is agranulocytosis, a severe depletion of white blood cells that leaves patients vulnerable to infection.

Dr. Sampaio said the victims suffered from open sores, hair loss, burns and severe depletion of white blood cells.

Data from Sept. 15 show the worst depletion at center, with less severe depletion indicated by successively lighter shades.

An ozone hole is a severe depletion of ozone for a period of time in a particular place, as occurs over Antarctica.

Reported severe depletion of large marine animals over the past 50 to 500 years.

The "ozone hole" is a severe depletion of the ozone layer high above Antarctica.

Awareness of Problem The first indications of a severe global depletion have been circulating among atmospheric scientists for a year.