Subjects with an incomplete examination of the large bowel, severe dysplasia, or carcinoma in situ were excluded.
It is possible that overdiagnosis and overtreatment of Barrett esophagus, particularly without severe dysplasia, could lead to a substantial number of harms.
Laser treatment is used in severe dysplasia, while overt malignancy may require surgery, radiation therapy, or systemic chemotherapy.
Mutations in the POP1 gene result in severe anauxetic dysplasia.
A Cone biopsy was performed and revealed severe dysplasia.
No severe or moderate dysplasia was seen in any of the patients examined.
None, however, had severe dysplasia.
Generally dysplasia is subjectively graded by pathologists into mild, moderate or severe dysplasia.
Often if biopsy demonstrates moderate or severe dysplasia then the decision to excise them is taken more readily.
Stage 2 is moderate dysplasia and stage 3 is severe dysplasia or early cancer.