Despite the case's enduring lack of evidence, a few significant clues have arisen.

But no significant new clues have been found.

But the really significant clue is the one of the crutch.

A search of her house uncovered no significant clues.

If he had hesitated at a crucial moment, he would have given the defenders a significant clue.

Sulgrove as West now had a significant negative clue.

Some of the most significant clues at first glance are:

There was one other small but significant clue.

The increase or decrease of this figure over time is a significant clue to the direction of cultural change in the society.

It gives very significant clues to his fascination with sexual ambiguity.