No one benefits from the very real, serious and significant diseases caused by smoking.
In small numbers, C. difficile does not result in significant disease.
By 1982 it was considered to be one of the more significant diseases of the peanut.
The disease is one of the most significant diseases of cucurbits worldwide.
All of these viruses cause significant disease in humans.
These organisms frequently are human pathogens that cause a wide spectrum of clinically significant disease.
Usually this is in response to a significant systemic disease and will subside once the person has recovered.
Happily, significant testicular disease is uncommon and usually not serious.
One of the most significant diseases that arise from poor sanitation is diarrhea.
When the recipient carries a significant genetic disease, relieving the child from fear of being a carrier.