But there is a more subtle and significant distinction, which causes much confusion.

The most significant distinction between bands is at the 2,000-mile mark.

Yet there is no discussion - indeed not even a mention - of this significant distinction.

"We consider that to be not a significant distinction."

They tended not to highlight the significant distinction between the two groups.

There are, however, many significant distinctions and the same tools can be applied in different ways.

Eventually he seems unable to make any significant distinction between reality and storyline.

And it is a program, not a department, a significant distinction.

Still, there are some significant distinctions in the roles of men and women.

This is not a particularly useful definition given the significant distinction between ownership and control.