One significant indication of this may be mentioned.
The report was the first significant indication of the state of the economy last month.
It was the first truly significant indication of how far he should be believed.
Those voices, rattling on quickly, were the first significant indication that they were in a foreign land.
Olfactory memory deficits can be significant indications of a number of things going on within the brain.
The contest for the Democratic nomination was, however, expected to provide significant indications of the party's aspirations in the final decade of the 20th century.
There were no significant indications of love.
Western officials welcomed the invitation to visit the Shikhany plant as a significant indication of Soviet good will.
There were no other significant indications.
Then we have significant indications of his character.