He could speak with nine men at once and answer all their questions with a single reply.

He still hadn't received a single reply to his letters to Anne.

I've written six letters and not had a single reply.

I wrote to you for two years without receiving a single reply.

We haven't had a single reply from your British guests.

Questions: these should be open ended and not answerable with a simple single reply.

What more could he have done than written her a hundred times without receiving one single reply.

That garbled any single reply, but one word was repeated often enough to come through clearly.

He received not a single reply to his offer.

It is very frustrating to put in job applications at places all over town without getting a single reply from anyone.