"Certainly not," she said, managing to smile despite the catch in her voice.

The big man smiled despite the pain of his broken wrist.

Smiled at him despite the pain he knew she felt.

It made sense in a way, though he had to smile despite himself at the irony of the situation.

I smiled slightly, despite the burning pain in my side.

She smiled at that despite the seriousness of the situation.

Paul looked at her, his eyes tearing from the wind, but smiling despite it.

I'm smiling despite myself as I open the front door.

He smiled despite himself, thinking how suddenly young she had looked.

She made herself smile at him despite the sick feeling in her stomach.