Since then, even more specific quantitative assays were developed for its detection at pH 6.0.
But, he said, "we set up a very specific assay and, with our assay, the behavior is inherited."
As a result, many less sensitive but highly specific assays have been withdrawn from the market [39].
The 1930s also saw the rise of pharmacokinetics, and as such the desire for more specific assays.
Detection of ANXA1 (by immunocytochemical means) reportedly provides a simple, highly-sensitive and specific assay for the diagnosis of hairy cell leukemia.
The previous reports of these peptides used less specific assays and were strongly criticised as using unreliable methods that were prone to false positive results.
A more specific assay makes use of 2,4-dimethoxybenzaldehyde (DMBA), a product that reacts specifically with 1,3-and 1,3,5-substituted phenols (e.g., phlorotannins) to form a colored product.
Thus the Far Western technique provides a sensitive and specific assay for detection of proteins that can complex with CREB.
Islet cell autoantibodies are detected by conventional immunofluorescence, while the rest are measured with specific radiobinding assays.
'Each of our screens has built on the previous one by including more specific assays', explains Dahm.