Anastasio was one of the family's biggest earners, steering millions of dollars in kickbacks and payoffs into the family's coffers.
She was charged last month in a bid-rigging scheme, accused of steering millions of dollars to computer companies for bribes.
Premier helped start American Pharmaceutical, then steered millions of dollars in business to it.
The Republicans also steered millions of dollars to friendly nonprofit groups and state party organizations.
He has faced allegations that he steered millions in aid to the state medical school in return for a no-show job there.
They also want to steer millions of investors and consumers toward companies judged to be most sensitive to environmental concerns.
A federal grand jury said the two men plotted to steer millions of dollars from the $17 billion tobacco settlement to Mr. Murr as legal fees.
Last week, Premier also sold its stake in a generic drug company to which it had steered millions of dollars in business.
Napier serves on the Appropriations and Revenue Committee, which has enabled him to steer millions in state funds to his district over the years.
During the Bush administration, American officials praised Uganda's family-values policies and steered millions of dollars into abstinence programs.