Age (young or old) is not a contraindication to strong opioids.

Morphine, as the strong opioid of choice for the management of cancer pain, was used increasingly during the 1970s and 1980s.

Piritramide is a strong opioid and therefore is regulated much the same as morphine in all known jurisdictions.

For the first time, general practitioners began to prescribe strong, long-acting opioids to treat chronic noncancer pain.

They strongly advise against using strong opioids.

They discourage the use of strong opioids, and only recommend using them while they continue to provide improved pain and functioning.

With strong opioids, the dose depends on the amount of pain.

In other countries it is more common to use morphine or other strong opioids in these situations.

There is little evidence to indicate that one strong opioid is more effective than another.

The analgesia from scopolamine plus a strong opioid is deep enough to allow higher doses to be used as a form of anaesthesia.